Gene name: CCL18

Uniprot entry:

P55774

Protein names:

C-C motif chemokine 18 (Alternative macrophage activation-associated CC chemokine 1) (AMAC-1) (CC chemokine PARC) (Dendritic cell chemokine 1) (DC-CK1) (Macrophage inflammatory protein 4) (MIP-4) (Pulmonary and activation-regulated chemokine) (Small-inducible cytokine A18) [Cleaved into: CCL18(1-68); CCL18(3-69); CCL18(4-69)]

Protein sequence:

1_MKGLA 6_ AALLV 11_ LVCTM 16_ ALCSC 21_ AQVGT 26_ NKELC 31_ CLVYT 36_ SWQIP 41_ QKFIV 46_ DYSET 51_ SPQCP 56_ KPGVI 61_ LLTKR 66_ GRQIC 71_ ADPNK 76_ KWVQK 81_YISDL

Protein annotations

Protein functions:

1: Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses