Gene name: BID

Uniprot entry:

P55957

Protein names:

BH3-interacting domain death agonist (p22 BID) (BID) [Cleaved into: BH3-interacting domain death agonist p15 (p15 BID); BH3-interacting domain death agonist p13 (p13 BID); BH3-interacting domain death agonist p11 (p11 BID)]

Protein sequence:

1_MDCEV 6_ NNGSS 11_ LRDEC 16_ ITNLL 21_ VFGFL 26_ QSCSD 31_ NSFRR 36_ ELDAL 41_ GHELP 46_ VLAPQ 51_ WEGYD 56_ ELQTD 61_ GNRSS 66_ HSRLG 71_ RIEAD 76_ SESQE 81_ DIIRN 86_ IARHL 91_ AQVGD 96_ SMDRS 101_ IPPGL 106_ VNGLA 111_ LQLRN 116_ TSRSE 121_ EDRNR 126_ DLATA 131_ LEQLL 136_ QAYPR 141_ DMEKE 146_ KTMLV 151_ LALLL 156_ AKKVA 161_ SHTPS 166_ LLRDV 171_ FHTTV 176_ NFINQ 181_ NLRTY 186_VRSLA

Protein annotations

Protein functions:

1: Induces caspases and apoptosis (PubMed:14583606). Counters the protective effect of BCL2 (By similarity)

2: Induces caspase activation and apoptosis (PubMed:15661737, PubMed:32029622). Allows the release of cytochrome c (PubMed:32029622)

3: Induces ICE-like proteases and apoptosis

4: Induces ICE-like proteases and apoptosis

5: Does not induce apoptosis

6: Induces ICE-like proteases and apoptosis