Caveolin-3 (M-caveolin)
1_MMAEE 6_ HTDLE 11_ AQIVK 16_ DIHCK 21_ EIDLV 26_ NRDPK 31_ NINED 36_ IVKVD 41_ FEDVI 46_ AEPVG 51_ TYSFD 56_ GVWKV 61_ SYTTF 66_ TVSKY 71_ WCYRL 76_ LSTLL 81_ GVPLA 86_ LLWGF 91_ LFACI 96_ SFCHI 101_ WAVVP 106_ CIKSY 111_ LIEIQ 116_ CISHI 121_ YSLCI 126_ RTFCN 131_ PLFAA 136_ LGQVC 141_ SSIKV 146_VLRKE
1: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity). Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae (PubMed:19262564)