ADP-ribosylation factor-like protein 4C (ADP-ribosylation factor-like protein 7) (ADP-ribosylation factor-like protein LAK)
1_MGNIS 6_ SNISA 11_ FQSLH 16_ IVMLG 21_ LDSAG 26_ KTTVL 31_ YRLKF 36_ NEFVN 41_ TVPTI 46_ GFNTE 51_ KIKLS 56_ NGTAK 61_ GISCH 66_ FWDVG 71_ GQEKL 76_ RPLWK 81_ SYSRC 86_ TDGII 91_ YVVDS 96_ VDVDR 101_ LEEAK 106_ TELHK 111_ VTKFA 116_ ENQGT 121_ PLLVI 126_ ANKQD 131_ LPKSL 136_ PVAEI 141_ EKQLA 146_ LHELI 151_ PATTY 156_ HVQPA 161_ CAIIG 166_ EGLTE 171_ GMDKL 176_ YEMIL 181_ KRRKS 186_LKQKK
1: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. May be involved in transport between a perinuclear compartment and the plasma membrane, apparently linked to the ABCA1-mediated cholesterol secretion pathway. Recruits CYTH1, CYTH2, CYTH3 and CYTH4 to the plasma membrane in the GDP-bound form. Regulates the microtubule-dependent intracellular vesicular transport from early endosome to recycling endosome process