Transcription factor SOX-10
1_MAEEQ 6_ DLSEV 11_ ELSPV 16_ GSEEP 21_ RCLSP 26_ GSAPS 31_ LGPDG 36_ GGGGS 41_ GLRAS 46_ PGPGE 51_ LGKVK 56_ KEQQD 61_ GEADD 66_ DKFPV 71_ CIREA 76_ VSQVL 81_ SGYDW 86_ TLVPM 91_ PVRVN 96_ GASKS 101_ KPHVK 106_ RPMNA 111_ FMVWA 116_ QAARR 121_ KLADQ 126_ YPHLH 131_ NAELS 136_ KTLGK 141_ LWRLL 146_ NESDK 151_ RPFIE 156_ EAERL 161_ RMQHK 166_ KDHPD 171_ YKYQP 176_ RRRKN 181_ GKAAQ 186_ GEAEC 191_ PGGEA 196_ EQGGT 201_ AAIQA 206_ HYKSA 211_ HLDHR 216_ HPGEG 221_ SPMSD 226_ GNPEH 231_ PSGQS 236_ HGPPT 241_ PPTTP 246_ KTELQ 251_ SGKAD 256_ PKRDG 261_ RSMGE 266_ GGKPH 271_ IDFGN 276_ VDIGE 281_ ISHEV 286_ MSNME 291_ TFDVA 296_ ELDQY 301_ LPPNG 306_ HPGHV 311_ SSYSA 316_ AGYGL 321_ GSALA 326_ VASGH 331_ SAWIS 336_ KPPGV 341_ ALPTV 346_ SPPGV 351_ DAKAQ 356_ VKTET 361_ AGPQG 366_ PPHYT 371_ DQPST 376_ SQIAY 381_ TSLSL 386_ PHYGS 391_ AFPSI 396_ SRPQF 401_ DYSDH 406_ QPSGP 411_ YYGHS 416_ GQASG 421_ LYSAF 426_ SYMGP 431_ SQRPL 436_ YTAIS 441_ DPSPS 446_ GPQSH 451_ SPTHW 456_ EQPVY 461_TTLSR
1: Transcription factor that plays a central role in developing and mature glia (By similarity). Specifically activates expression of myelin genes, during oligodendrocyte (OL) maturation, such as DUSP15 and MYRF, thereby playing a central role in oligodendrocyte maturation and CNS myelination (By similarity). Once induced, MYRF cooperates with SOX10 to implement the myelination program (By similarity). Transcriptional activator of MITF, acting synergistically with PAX3 (PubMed:21965087). Transcriptional activator of MBP, via binding to the gene promoter (By similarity)