Protein Wnt-4
1_MSPRS 6_ CLRSL 11_ RLLVF 16_ AVFSA 21_ AASNW 26_ LYLAK 31_ LSSVG 36_ SISEE 41_ ETCEK 46_ LKGLI 51_ QRQVQ 56_ MCKRN 61_ LEVMD 66_ SVRRG 71_ AQLAI 76_ EECQY 81_ QFRNR 86_ RWNCS 91_ TLDSL 96_ PVFGK 101_ VVTQG 106_ TREAA 111_ FVYAI 116_ SSAGV 121_ AFAVT 126_ RACSS 131_ GELEK 136_ CGCDR 141_ TVHGV 146_ SPQGF 151_ QWSGC 156_ SDNIA 161_ YGVAF 166_ SQSFV 171_ DVRER 176_ SKGAS 181_ SSRAL 186_ MNLHN 191_ NEAGR 196_ KAILT 201_ HMRVE 206_ CKCHG 211_ VSGSC 216_ EVKTC 221_ WRAVP 226_ PFRQV 231_ GHALK 236_ EKFDG 241_ ATEVE 246_ PRRVG 251_ SSRAL 256_ VPRNA 261_ QFKPH 266_ TDEDL 271_ VYLEP 276_ SPDFC 281_ EQDMR 286_ SGVLG 291_ TRGRT 296_ CNKTS 301_ KAIDG 306_ CELLC 311_ CGRGF 316_ HTAQV 321_ ELAER 326_ CSCKF 331_ HWCCF 336_ VKCRQ 341_ CQRLV 346_ELHTC
1: Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Plays an important role in the embryonic development of the urogenital tract and the lung (PubMed:15317892, PubMed:16959810, PubMed:18179883, PubMed:18182450). Required for normal mesenchyme to epithelium transition during embryonic kidney development. Required for the formation of early epithelial renal vesicles during kidney development (By similarity). Required for normal formation of the Mullerian duct in females, and normal levels of oocytes in the ovaries (PubMed:15317892, PubMed:16959810, PubMed:18182450). Required for normal down-regulation of 3 beta-hydroxysteroid dehydrogenase in the ovary (PubMed:15317892, PubMed:16959810, PubMed:18182450). Required for normal lung development and for normal patterning of trachael cartilage rings (By similarity)