Gene name: CLDN8

Uniprot entry:

P56748

Protein names:

Claudin-8

Protein sequence:

1_MATHA 6_ LEIAG 11_ LFLGG 16_ VGMVG 21_ TVAVT 26_ VMPQW 31_ RVSAF 36_ IENNI 41_ VVFEN 46_ FWEGL 51_ WMNCV 56_ RQANI 61_ RMQCK 66_ IYDSL 71_ LALSP 76_ DLQAA 81_ RGLMC 86_ AASVM 91_ SFLAF 96_ MMAIL 101_ GMKCT 106_ RCTGD 111_ NEKVK 116_ AHILL 121_ TAGII 126_ FIITG 131_ MVVLI 136_ PVSWV 141_ ANAII 146_ RDFYN 151_ SIVNV 156_ AQKRE 161_ LGEAL 166_ YLGWT 171_ TALVL 176_ IVGGA 181_ LFCCV 186_ FCCNE 191_ KSSSY 196_ RYSIP 201_ SHRTT 206_ QKSYH 211_ TGKKS 216_PSVYS

Protein annotations

Protein functions:

1: Can associate with other claudins to regulate tight junction structural and functional strand dynamics (By similarity). May coassemble with CLDN4 into tight junction strands containing anion-selective channels that convey paracellular chloride permeability in renal collecting ducts (By similarity) (PubMed:36008380). Cannot form tight junction strands on its own (PubMed:36008380)