Claudin-17
1_MAFYP 6_ LQIAG 11_ LVLGF 16_ LGMVG 21_ TLATT 26_ LLPQW 31_ RVSAF 36_ VGSNI 41_ IVFER 46_ LWEGL 51_ WMNCI 56_ RQARV 61_ RLQCK 66_ FYSSL 71_ LALPP 76_ ALETA 81_ RALMC 86_ VAVAL 91_ SLIAL 96_ LIGIC 101_ GMKQV 106_ QCTGS 111_ NERAK 116_ AYLLG 121_ TSGVL 126_ FILTG 131_ IFVLI 136_ PVSWT 141_ ANIII 146_ RDFYN 151_ PAIHI 156_ GQKRE 161_ LGAAL 166_ FLGWA 171_ SAAVL 176_ FIGGG 181_ LLCGF 186_ CCCNR 191_ KKQGY 196_ RYPVP 201_ GYRVP 206_ HTDKR 211_ RNTTM 216_LSKTS
1: Channel-forming tight junction protein with selectivity for anions, including chloride and hydrogencarbonate, and for solutes smaller than 9 Angstrom in diameter. In the kidney proximal tubule, may be involved in paracellular reabsorption of filtered anions. Does not affect water permeability