Cilia- and flagella-associated protein 298 (Protein kurly homolog)
1_MVLLH 6_ VKRGD 11_ ESQFL 16_ LQAPG 21_ STELE 26_ ELTVQ 31_ VARVY 36_ NGRLK 41_ VQRLC 46_ SEMEE 51_ LAEHG 56_ IFLPP 61_ NMQGL 66_ TDDQI 71_ EELKL 76_ KDEWG 81_ EKCVP 86_ SGGAV 91_ FKKDD 96_ IGRRN 101_ GQAPN 106_ EKMKQ 111_ VLKKT 116_ IEEAK 121_ AIISK 126_ KQVEA 131_ GVCVT 136_ MEMVK 141_ DALDQ 146_ LRGAV 151_ MIVYP 156_ MGLPP 161_ YDPIR 166_ MEFEN 171_ KEDLS 176_ GTQAG 181_ LNVIK 186_ EAEAQ 191_ LWWAA 196_ KELRR 201_ TKKLS 206_ DYVGK 211_ NEKTK 216_ IIAKI 221_ QQRGQ 226_ GAPAR 231_ EPIIS 236_ SEEQK 241_ QLMLY 246_ YHRRQ 251_ EELKR 256_ LEEND 261_ DDAYL 266_ NSPWA 271_ DNTAL 276_ KRHFH 281_GVKDI
1: Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly (PubMed:24094744). Seems to be important for initiation rather than maintenance of cilium motility (By similarity). Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (By similarity). May suppress canonical Wnt signaling activity (By similarity)