Gene name: EVC

Uniprot entry:

P57679

Protein names:

Ellis-van Creveld syndrome protein (DWF-1)

Protein sequence:

1_MARGG 6_ AACKS 11_ DARLL 16_ LGRDA 21_ LRPAP 26_ ALLAP 31_ AVLLG 36_ AALGL 41_ GLGLW 46_ LGCRA 51_ GRQRT 56_ RHQKD 61_ DTQNL 66_ LKNLE 71_ SNAQT 76_ PSETG 81_ SPSRR 86_ RKREV 91_ QMSKD 96_ KEAVD 101_ ECEPP 106_ SNSNI 111_ TAFAL 116_ KAKVI 121_ YPINQ 126_ KFRPL 131_ ADGSS 136_ NPSLH 141_ ENLKQ 146_ AVLPH 151_ QPVEA 156_ SPSSS 161_ LGSLS 166_ QGEKD 171_ DCSSS 176_ SSVHS 181_ ATSDD 186_ RFLSR 191_ TFLRV 196_ NAFPE 201_ VLACE 206_ SVDVD 211_ LCIYS 216_ LHLKD 221_ LLHLD 226_ TALRQ 231_ EKHMM 236_ FIQIF 241_ KMCLL 246_ DLLPK 251_ KKSDD 256_ ELYQK 261_ ILSKQ 266_ EKDLE 271_ ELEKG 276_ LQVKL 281_ SNTEM 286_ SGAGD 291_ SEYIT 296_ LADVE 301_ KKERE 306_ YSEQL 311_ IDNME 316_ AFWKQ 321_ MANIQ 326_ HFLVD 331_ QFKCS 336_ SSKAR 341_ QLMMT 346_ LTERM 351_ IAAEG 356_ LLCDS 361_ QELQA 366_ LDALE 371_ RTMGR 376_ AHMAK 381_ VIEFL 386_ KLQVQ 391_ EETRC 396_ RLAAI 401_ SHGLE 406_ LLAGE 411_ GKLSG 416_ RQKEE 421_ LLTQQ 426_ HKAFW 431_ QEAER 436_ FSREF 441_ VQRGK 446_ DLVTA 451_ SLAHQ 456_ VEGTA 461_ KLTLA 466_ QEEEQ 471_ RSFLA 476_ EAQPT 481_ ADPEK 486_ FLEAF 491_ HEVLE 496_ RQRLM 501_ QCDLE 506_ EEENV 511_ RATEA 516_ VVALC 521_ QELYF 526_ STVDT 531_ FQKFV 536_ DALFL 541_ QTLPG 546_ MTGLP 551_ PEECD 556_ YLRQE 561_ VQENA 566_ AWQLG 571_ KSNRF 576_ RRQQW 581_ KLFQE 586_ LLEQD 591_ QQVWM 596_ EECAL 601_ SSVLQ 606_ THLRE 611_ DHEGT 616_ IRGVL 621_ GRLGG 626_ LTEES 631_ TRCVL 636_ QGHDL 641_ LLRSA 646_ LRRLA 651_ LRGNA 656_ LATLT 661_ QMRLS 666_ GKKHL 671_ LQELR 676_ EQRAL 681_ EQGSS 686_ QCLDE 691_ HQWQL 696_ LRALE 701_ ARVLE 706_ EASRL 711_ EEEAQ 716_ QTRLQ 721_ LQQRL 726_ LAEAQ 731_ EVGQL 736_ LQQHM 741_ ECAIG 746_ QALLV 751_ HARNA 756_ ATKSR 761_ AKDRD 766_ DFKRT 771_ LMEAA 776_ VESVY 781_ VTSAG 786_ VSRLV 791_ QAYYQ 796_ QIGRI 801_ MEDHE 806_ ERKLQ 811_ HLKTL 816_ QGERM 821_ ENYKL 826_ RKKQE 831_ LSNPS 836_ SGSRT 841_ AGGAH 846_ ETSQA 851_ VHQRM 856_ LSQQK 861_ RFLAQ 866_ FPVHQ 871_ QMRLH 876_ AQQQQ 881_ AGVMD 886_ LLEAQ 891_ LETQL 896_ QEAEQ 901_ NFISE 906_ LAALA 911_ RVPLA 916_ ESKLL 921_ PAKRG 926_ LLEKP 931_ LRTKR 936_ KKPLP 941_ QERGD 946_ LGVPN 951_ NEDLA 956_ SGDQT 961_ SGSLS 966_ SKRLS 971_ QQESE 976_ AGDSG 981_ NSKKM 986_LKRRS

Protein annotations

Protein functions:

1: Component of the EvC complex that positively regulates ciliary Hedgehog (Hh) signaling. Involved in endochondral growth and skeletal development