Gene name: CARD18

Uniprot entry:

P57730

Protein names:

Caspase recruitment domain-containing protein 18 (Caspase-1 inhibitor Iceberg)

Protein sequence:

1_MADQL 6_ LRKKR 11_ RIFIH 16_ SVGAG 21_ TINAL 26_ LDCLL 31_ EDEVI 36_ SQEDM 41_ NKVRD 46_ ENDTV 51_ MDKAR 56_ VLIDL 61_ VTGKG 66_ PKSCC 71_ KFIKH 76_ LCEED 81_PQLAS

Protein annotations

Protein functions:

1: Inhibits generation of IL-1-beta by interacting with caspase-1 and preventing its association with RIP2. Down-regulates the release of IL1B