Gene name: RGS8

Uniprot entry:

P57771

Protein names:

Regulator of G-protein signaling 8 (RGS8)

Protein sequence:

1_MAALL 6_ MPRRN 11_ KGMRT 16_ RLGCL 21_ SHKSD 26_ SCSDF 31_ TAILP 36_ DKPNR 41_ ALKRL 46_ STEEA 51_ TRWAD 56_ SFDVL 61_ LSHKY 66_ GVAAF 71_ RAFLK 76_ TEFSE 81_ ENLEF 86_ WLACE 91_ EFKKT 96_ RSTAK 101_ LVSKA 106_ HRIFE 111_ EFVDV 116_ QAPRE 121_ VNIDF 126_ QTREA 131_ TRKNL 136_ QEPSL 141_ TCFDQ 146_ AQGKV 151_ HSLME 156_ KDSYP 161_ RFLRS 166_ KMYLD 171_LLSQS

Protein annotations

Protein functions:

1: Regulates G protein-coupled receptor signaling cascades, including signaling via muscarinic acetylcholine receptor CHRM2 and dopamine receptor DRD2 (By similarity). Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form (PubMed:18434541). Modulates the activity of potassium channels that are activated in response to DRD2 and CHRM2 signaling (By similarity)