Neurexin-1-beta (Neurexin I-beta)
1_MYQRM 6_ LRCGA 11_ ELGSP 16_ GGGGG 21_ GGGGG 26_ GAGGR 31_ LALLW 36_ IVPLT 41_ LSGLL 46_ GVAWG 51_ ASSLG 56_ AHHIH 61_ HFHGS 66_ SKHHS 71_ VPIAI 76_ YRSPA 81_ SLRGG 86_ HAGTT 91_ YIFSK 96_ GGGQI 101_ TYKWP 106_ PNDRP 111_ STRAD 116_ RLAIG 121_ FSTVQ 126_ KEAVL 131_ VRVDS 136_ SSGLG 141_ DYLEL 146_ HIHQG 151_ KIGVK 156_ FNVGT 161_ DDIAI 166_ EESNA 171_ IINDG 176_ KYHVV 181_ RFTRS 186_ GGNAT 191_ LQVDS 196_ WPVIE 201_ RYPAG 206_ NNDNE 211_ RLAIA 216_ RQRIP 221_ YRLGR 226_ VVDEW 231_ LLDKG 236_ RQLTI 241_ FNSQA 246_ TIIIG 251_ GKEQG 256_ QPFQG 261_ QLSGL 266_ YYNGL 271_ KVLNM 276_ AAEND 281_ ANIAI 286_ VGNVR 291_ LVGEV 296_ PSSMT 301_ TESTA 306_ TAMQS 311_ EMSTS 316_ IMETT 321_ TTLAT 326_ STARR 331_ GKPPT 336_ KEPIS 341_ QTTDD 346_ ILVAS 351_ AECPS 356_ DDEDI 361_ DPCEP 366_ SSGGL 371_ ANPTR 376_ AGGRE 381_ PYPGS 386_ AEVIR 391_ ESSST 396_ TGMVV 401_ GIVAA 406_ AALCI 411_ LILLY 416_ AMYKY 421_ RNRDE 426_ GSYHV 431_ DESRN 436_ YISNS 441_ AQSNG 446_ AVVKE 451_ KQPSS 456_ AKSSN 461_ KNKKN 466_KDKEY
1: Neuronal cell surface protein involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins (By similarity). Plays a role in formation of synaptic junctions (By similarity). Functions as part of a trans-synaptic complex by binding to cerebellins and postsynaptic GRID1. This interaction helps regulate the activity of NMDA and AMPA receptors at hippocampal synapses without affecting synapse formation. NRXN1B-CBLN2-GRID1 complex transduce presynaptic signals into postsynaptic NMDAR response (By similarity)