Ras-related protein Rab-15
1_MAKQY 6_ DVLFR 11_ LLLIG 16_ DSGVG 21_ KTCLL 26_ CRFTD 31_ NEFHS 36_ SHIST 41_ IGVDF 46_ KMKTI 51_ EVDGI 56_ KVRIQ 61_ IWDTA 66_ GQERY 71_ QTITK 76_ QYYRR 81_ AQGIF 86_ LVYDI 91_ SSERS 96_ YQHIM 101_ KWVSD 106_ VDEYA 111_ PEGVQ 116_ KILIG 121_ NKADE 126_ EQKRQ 131_ VGREQ 136_ GQQLA 141_ KEYGM 146_ DFYET 151_ SACTN 156_ LNIKE 161_ SFTRL 166_ TELVL 171_ QAHRK 176_ ELEGL 181_ RMRAS 186_ NELAL 191_ AELEE 196_ EEGKP 201_ EGPAN 206_SSKTC
1: The small GTPases Rab are key regulators of intracellular membrane trafficking, from the formation of transport vesicles to their fusion with membranes (By similarity). Rabs cycle between an inactive GDP-bound form and an active GTP-bound form that is able to recruit to membranes different sets of downstream effectors directly responsible for vesicle formation, movement, tethering and fusion (By similarity). RAB15 may act in concert with RAB3A in regulating aspects of synaptic vesicle membrane flow within the nerve terminal (By similarity)