Taste receptor type 2 member 46 (T2R46) (Taste receptor type 2 member 54) (T2R54)
1_MITFL 6_ PIIFS 11_ ILIVV 16_ TFVIG 21_ NFANG 26_ FIALV 31_ NSIEW 36_ FKRQK 41_ ISFAD 46_ QILTA 51_ LAVSR 56_ VGLLW 61_ VLVLN 66_ WYATE 71_ LNPAF 76_ NSIEV 81_ RITAY 86_ NVWAV 91_ INHFS 96_ NWLAT 101_ SLSIF 106_ YLLKI 111_ ANFSN 116_ LIFLH 121_ LKRRV 126_ KSVVL 131_ VILLG 136_ PLLFL 141_ VCHLF 146_ VINMN 151_ QIIWT 156_ KEYEG 161_ NMTWK 166_ IKLRS 171_ AMYLS 176_ NTTVT 181_ ILANL 186_ VPFTL 191_ TLISF 196_ LLLIC 201_ SLCKH 206_ LKKMQ 211_ LHGKG 216_ SQDPS 221_ MKVHI 226_ KALQT 231_ VTSFL 236_ LLCAI 241_ YFLSI 246_ IMSVW 251_ SFESL 256_ ENKPV 261_ FMFCE 266_ AIAFS 271_ YPSTH 276_ PFILI 281_ WGNKK 286_ LKQTF 291_ LSVLW 296_ HVRYW 301_VKGEK
1: Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity). In airway epithelial cells, binding of bitter compounds increases the intracellular calcium ion concentration and stimulates ciliary beat frequency (By similarity)