Keratin-associated protein 12-2 (High sulfur keratin-associated protein 12.2) (Keratin-associated protein 12.2)
1_MCHTS 6_ CSSGC 11_ QPACC 16_ APSPC 21_ QPACC 26_ VPSSC 31_ QASCC 36_ VPVGC 41_ QSSVC 46_ VPVSF 51_ KPAVC 56_ LPVSC 61_ QSSVC 66_ VPMSF 71_ KSAVC 76_ VPVSC 81_ QSSVC 86_ VPVSC 91_ RPIVC 96_ AAPSC 101_ QSSLC 106_ VPVSC 111_ RPVVY 116_ AAPSC 121_ QSSGC 126_ CQPSC 131_ TSVLC 136_ RPISY 141_SISSC
1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins