Beta-defensin 1 (BD-1) (hBD-1) (Defensin, beta 1)
1_MRTSY 6_ LLLFT 11_ LCLLL 16_ SEMAS 21_ GGNFL 26_ TGLGH 31_ RSDHY 36_ NCVSS 41_ GGQCL 46_ YSACP 51_ IFTKI 56_ QGTCY 61_RGKAK
1: Has bactericidal activity. May act as a ligand for C-C chemokine receptor CCR6. Positively regulates the sperm motility and bactericidal activity in a CCR6-dependent manner. Binds to CCR6 and triggers Ca2+ mobilization in the sperm which is important for its motility (PubMed:25122636)