Nanos homolog 3 (NOS-3)
1_MGTFD 6_ LWTDY 11_ LGLAH 16_ LVRAL 21_ SGKEG 26_ PETRL 31_ SPQPE 36_ PEPML 41_ EPDQK 46_ RSLES 51_ SPAPE 56_ RLCSF 61_ CKHNG 66_ ESRAI 71_ YQSHV 76_ LKDEA 81_ GRVLC 86_ PILRD 91_ YVCPQ 96_ CGATR 101_ ERAHT 106_ RRFCP 111_ LTGQG 116_ YTSVY 121_ SHTTR 126_ NSAGK 131_ KLVRP 136_ DKAKT 141_ QDTGH 146_ RRGGG 151_ GGAGF 156_ RGAGK 161_ SEPSP 166_SCSPS
1: Plays a role in the maintenance of the undifferentiated state of germ cells regulating the spermatogonia cell cycle and inducing a prolonged transit in G1 phase. Affects cell proliferation probably by repressing translation of specific mRNAs. Maintains the germ cell lineage by suppressing both Bax-dependent and -independent apoptotic pathways. Essential in the early stage embryo to protect the migrating primordial germ cells (PGCs) from apoptosis