Gene name: KRTAP12-4

Uniprot entry:

P60329

Protein names:

Keratin-associated protein 12-4 (High sulfur keratin-associated protein 12.4) (Keratin-associated protein 12.4)

Protein sequence:

1_MCHTS 6_ HSSGC 11_ PMACP 16_ GSPCC 21_ VPSTC 26_ YPPEG 31_ YGTSC 36_ CCSAP 41_ CVALL 46_ CRPLC 51_ GVSTC 56_ CQPAC 61_ CVPSP 66_ CQVAC 71_ CVPVS 76_ CKPVL 81_ CVASF 86_ CPTSG 91_ CCQPF 96_ CPTLV 101_ YRPVT 106_WSTPT

Protein annotations

Protein functions:

1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins