Gene name: KRTAP10-4

Uniprot entry:

P60372

Protein names:

Keratin-associated protein 10-4 (High sulfur keratin-associated protein 10.4) (Keratin-associated protein 10.4) (Keratin-associated protein 18-4) (Keratin-associated protein 18.4)

Protein sequence:

1_MSVCS 6_ SDLSY 11_ SSRVC 16_ LPGSC 21_ DSCSD 26_ SWQVD 31_ DCPES 36_ CCEPP 41_ CCAPS 46_ CCAPA 51_ PCLSL 56_ VCTPV 61_ SRVSS 66_ PCCPV 71_ TCEPS 76_ PCQSG 81_ CTSSC 86_ TPSCC 91_ QQSSC 96_ QLACC 101_ ASSPC 106_ QQACC 111_ VPVCC 116_ KTVCC 121_ KPVCC 126_ VPVCC 131_ GDSSC 136_ CQQSS 141_ CQSAC 146_ CTSSP 151_ CQQAC 156_ CVPIC 161_ CKPVC 166_ SGISS 171_ SCCQQ 176_ SSCVS 181_ CVSSP 186_ CCQAV 191_ CEPSP 196_ CQSGC 201_ ISSCT 206_ PSCCQ 211_ QSSCQ 216_ PACCT 221_ SSSCQ 226_ QACCV 231_ PVCCK 236_ TVCCK 241_ PVCSE 246_ DSSSC 251_ CQQSS 256_ CQPAC 261_ CTSSP 266_ CQQAC 271_ CVPVC 276_ CKPVC 281_ CKPVG 286_ SVPIC 291_ SGASS 296_ LCCQQ 301_ SSCQP 306_ ACCTS 311_ SQSQQ 316_ GCCVP 321_ VCCKP 326_ VSCVP 331_ VCSGA 336_ SSSCC 341_ QQSSC 346_ QPACC 351_ TTSCC 356_ RPSSS 361_ VSLLC 366_ RPVCR 371_ PACCV 376_ PVPSC 381_ CAPTS 386_ SCQPS 391_ CCRPA 396_SCVSL

Protein annotations

Protein functions:

1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins