Gene name: KRTAP10-11

Uniprot entry:

P60412

Protein names:

Keratin-associated protein 10-11 (High sulfur keratin-associated protein 10.11) (Keratin-associated protein 10.11) (Keratin-associated protein 18-11) (Keratin-associated protein 18.11)

Protein sequence:

1_MAAST 6_ MSVCS 11_ SAYSD 16_ SWQVD 21_ DCPES 26_ CCEPP 31_ CSAPS 36_ CCAPA 41_ PSLSL 46_ VCTPV 51_ SCVSS 56_ PCCQA 61_ ACEPS 66_ ACQSG 71_ CTSSC 76_ TPSCC 81_ QQSSC 86_ QPACC 91_ TSSPC 96_ QQACC 101_ VPVCC 106_ KTVCC 111_ KPVCC 116_ VPVCC 121_ GAASS 126_ CCRQS 131_ SCQPA 136_ CCASS 141_ SCQPA 146_ CCVPV 151_ CCKPV 156_ CCVST 161_ CSEDS 166_ SSCCQ 171_ QSSCQ 176_ PACCT 181_ SSSYQ 186_ QACCV 191_ PVCCK 196_ TVYCK 201_ PICCV 206_ PVCSR 211_ ASSSR 216_ CQQPS 221_ CQPAC 226_ CTTSC 231_ CRPSS 236_ SVSLL 241_ CHPVC 246_ RSTCC 251_ VPVSS 256_ CCAPT 261_ SSCQS 266_ SCCRP 271_ ASCVS 276_ LLCRP 281_ ASSRL 286_ ACYSL 291_CSGKK

Protein annotations

Protein functions:

1: In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated proteins (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high-sulfur and high-glycine-tyrosine keratins