Endogenous retrovirus group FC1 Env polyprotein (Envelope polyprotein) (Fc1env) (HERV-F(c)1_Xq21.33 provirus ancestral Env polyprotein) (HERV-Fc1env) [Cleaved into: Surface protein (SU); Transmembrane protein (TM)]
1_MARPS 6_ PLCLL 11_ LLLTL 16_ LTPIV 21_ PSNSL 26_ LTEPP 31_ FRWRF 36_ YLHET 41_ WTQGN 46_ RLSTV 51_ TLATV 56_ DCQPH 61_ GCQAQ 66_ VTFNF 71_ TSFKS 76_ VLRGW 81_ SNPTI 86_ CFVYD 91_ QTHSN 96_ CRDYW 101_ VDTNG 106_ GCPYA 111_ YCRMH 116_ VTQLH 121_ TAKKL 126_ QHTYR 131_ LTSDG 136_ RTTYF 141_ LTIPD 146_ PWDSR 151_ WVSGV 156_ TGRLY 161_ RWPTD 166_ SYPVG 171_ KLRIF 176_ LTYIR 181_ VIPQV 186_ LSNLK 191_ DQADN 196_ IKHQE 201_ EVINT 206_ LVQSH 211_ PKADM 216_ VTYDD 221_ KAEAG 226_ PFSWI 231_ TLVRH 236_ GARLV 241_ NMAGL 246_ VNLSH 251_ CFLCT 256_ ALSQP 261_ PLVAV 266_ PLPQA 271_ FNTSG 276_ NHTAH 281_ PSGVF 286_ SEQVP 291_ LFRDP 296_ LQPQF 301_ PFCYT 306_ TPNSS 311_ WCNQT 316_ YSGSL 321_ SNLSA 326_ PAGGY 331_ FWCNF 336_ TLTKH 341_ LNISS 346_ NNTLS 351_ RNLCL 356_ PISLV 361_ PRLTL 366_ YSEAE 371_ LSSLV 376_ NPPMR 381_ QKRAV 386_ FPPLV 391_ IGVSL 396_ TSSLV 401_ ASGLG 406_ TGAIV 411_ HFISS 416_ SQDLS 421_ IKLQM 426_ AIEAS 431_ AESLA 436_ SLQRQ 441_ ITSVA 446_ KVAMQ 451_ NRRAL 456_ DLLTA 461_ DKGGT 466_ CMFLG 471_ EECCY 476_ YINES 481_ GLVET 486_ SLLTL 491_ DKIRD 496_ GLHRP 501_ SSTPN 506_ YGGGW 511_ WQSPL 516_ TTWII 521_ PFISP 526_ ILIIC 531_ LLLLI 536_ APCVL 541_ KFIKN 546_ RISEV 551_ SRVTV 556_ NQMLL 561_ HPYSR 566_ LPTSE 571_ DHYDD 576_ALTQQ
1: Retroviral envelope proteins mediate receptor recognition and membrane fusion during early infection. Endogenous envelope proteins may have kept, lost or modified their original function during evolution. This endogenous envelope protein has lost its original fusogenic properties
2: SU mediates receptor recognition
3: TM anchors the envelope heterodimer to the viral membrane through one transmembrane domain. The other hydrophobic domain, called fusion peptide, mediates fusion of the viral membrane with the target cell membrane (By similarity)