Pterin-4-alpha-carbinolamine dehydratase (PHS) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase) (Dimerization cofactor of hepatocyte nuclear factor 1-alpha) (DCoH) (Dimerization cofactor of HNF1) (Phenylalanine hydroxylase-stimulating protein) (Pterin carbinolamine dehydratase) (PCD)
1_MAGKA 6_ HRLSA 11_ EERDQ 16_ LLPNL 21_ RAVGW 26_ NELEG 31_ RDAIF 36_ KQFHF 41_ KDFNR 46_ AFGFM 51_ TRVAL 56_ QAEKL 61_ DHHPE 66_ WFNVY 71_ NKVHI 76_ TLSTH 81_ ECAGL 86_ SERDI 91_ NLASF 96_IEQVA
1: Involved in tetrahydrobiopterin biosynthesis (By similarity). Seems to both prevent the formation of 7-pterins and accelerate the formation of quinonoid-BH2. Coactivator for HNF1A-dependent transcription (By similarity). Regulates the dimerization of homeodomain protein HNF1A and enhances its transcriptional activity (By similarity). Also acts as a coactivator for HNF1B-dependent transcription (PubMed:24204001)