Gene name: HERV-K104

Uniprot entry:

P61576

Protein names:

Endogenous retrovirus group K member 104 Rec protein (HERV-K104 Rec protein) (HERV-K_5q13.3 provirus Rec protein)

Protein sequence:

1_MNPSE 6_ MQRKA 11_ PPRRR 16_ RHCNR 21_ APLTH 26_ KMNKM 31_ VTSEE 36_ EMKLP 41_ STKKA 46_ EPLTW 51_ AQLKK 56_ LTQLA 61_ TKCLE 66_ NTKVT 71_ QTPES 76_ MLLAA 81_ LMIVS 86_ MVSAG 91_ VTNSS 96_KETAT

Protein annotations

Protein functions:

1: Retroviral replication requires the nuclear export and translation of unspliced, singly-spliced and multiply-spliced derivatives of the initial genomic transcript. Rec interacts with a highly structured RNA element (RcRE) present in the viral 3'LTR and recruits the cellular nuclear export machinery. This permits export to the cytoplasm of unspliced genomic or incompletely spliced subgenomic viral transcripts (By similarity)