Gene name: ERVK-16

Uniprot entry:

P61578

Protein names:

Endogenous retrovirus group K member 16 Rec protein (HERV-K_10p14 provirus Rec protein)

Protein sequence:

1_MNPSE 6_ MQRKA 11_ PPRRR 16_ RHRNR 21_ APSSH 26_ KMNKM 31_ MMSEE 36_ QMKLP 41_ STNKA 46_ EPLTW 51_ AQLNK 56_ LTQLA 61_ TKCLE 66_ NTKMT 71_ QTPES 76_ MLLAA 81_ LMIVS 86_ TVSAG 91_ VPNSS 96_EETVT

Protein annotations

Protein functions:

1: Retroviral replication requires the nuclear export and translation of unspliced, singly-spliced and multiply-spliced derivatives of the initial genomic transcript. Rec interacts with a highly structured RNA element (RcRE) present in the viral 3'LTR and recruits the cellular nuclear export machinery. This permits export to the cytoplasm of unspliced genomic or incompletely spliced subgenomic viral transcripts (By similarity)