Coatomer subunit zeta-1 (Zeta-1-coat protein) (Zeta-1 COP)
1_MEALI 6_ LEPSL 11_ YTVKA 16_ ILILD 21_ NDGDR 26_ LFAKY 31_ YDDTY 36_ PSVKE 41_ QKAFE 46_ KNIFN 51_ KTHRT 56_ DSEIA 61_ LLEGL 66_ TVVYK 71_ SSIDL 76_ YFYVI 81_ GSSYE 86_ NELML 91_ MAVLN 96_ CLFDS 101_ LSQML 106_ RKNVE 111_ KRALL 116_ ENMEG 121_ LFLAV 126_ DEIVD 131_ GGVIL 136_ ESDPQ 141_ QVVHR 146_ VALRG 151_ EDVPL 156_ TEQTV 161_ SQVLQ 166_ SAKEQ 171_IKWSL
1: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins (By similarity). The zeta subunit may be involved in regulating the coat assembly and, hence, the rate of biosynthetic protein transport due to its association-dissociation properties with the coatomer complex (By similarity)