Neuronal calcium sensor 1 (NCS-1) (Frequenin homolog) (Frequenin-like protein) (Frequenin-like ubiquitous protein)
1_MGKSN 6_ SKLKP 11_ EVVEE 16_ LTRKT 21_ YFTEK 26_ EVQQW 31_ YKGFI 36_ KDCPS 41_ GQLDA 46_ AGFQK 51_ IYKQF 56_ FPFGD 61_ PTKFA 66_ TFVFN 71_ VFDEN 76_ KDGRI 81_ EFSEF 86_ IQALS 91_ VTSRG 96_ TLDEK 101_ LRWAF 106_ KLYDL 111_ DNDGY 116_ ITRNE 121_ MLDIV 126_ DAIYQ 131_ MVGNT 136_ VELPE 141_ EENTP 146_ EKRVD 151_ RIFAM 156_ MDKNA 161_ DGKLT 166_ LQEFQ 171_ EGSKA 176_ DPSIV 181_QALSL
1: Neuronal calcium sensor, regulator of G protein-coupled receptor phosphorylation in a calcium dependent manner. Directly regulates GRK1 (RHOK), but not GRK2 to GRK5. Can substitute for calmodulin (By similarity). Stimulates PI4KB kinase activity (By similarity). Involved in long-term synaptic plasticity through its interaction with PICK1 (By similarity). May also play a role in neuron differentiation through inhibition of the activity of N-type voltage-gated calcium channel (By similarity)