Ubiquitin-conjugating enzyme E2 G1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme G1) (E217K) (UBC7) (Ubiquitin carrier protein G1) (Ubiquitin-protein ligase G1) [Cleaved into: Ubiquitin-conjugating enzyme E2 G1, N-terminally processed]
1_MTELQ 6_ SALLL 11_ RRQLA 16_ ELNKN 21_ PVEGF 26_ SAGLI 31_ DDNDL 36_ YRWEV 41_ LIIGP 46_ PDTLY 51_ EGGVF 56_ KAHLT 61_ FPKDY 66_ PLRPP 71_ KMKFI 76_ TEIWH 81_ PNVDK 86_ NGDVC 91_ ISILH 96_ EPGED 101_ KYGYE 106_ KPEER 111_ WLPIH 116_ TVETI 121_ MISVI 126_ SMLAD 131_ PNGDS 136_ PANVD 141_ AAKEW 146_ REDRN 151_ GEFKR 156_ KVARC 161_VRKSQ
1: Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination. May be involved in degradation of muscle-specific proteins. Mediates polyubiquitination of CYP3A4