U6 snRNA-associated Sm-like protein LSm3
1_MADDV 6_ DQQQT 11_ TNTVE 16_ EPLDL 21_ IRLSL 26_ DERIY 31_ VKMRN 36_ DRELR 41_ GRLHA 46_ YDQHL 51_ NMILG 56_ DVEET 61_ VTTIE 66_ IDEET 71_ YEEIY 76_ KSTKR 81_ NIPML 86_ FVRGD 91_ GVVLV 96_APPLR
1: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320)