U6 snRNA-associated Sm-like protein LSm6
1_MSLRK 6_ QTPSD 11_ FLKQI 16_ IGRPV 21_ VVKLN 26_ SGVDY 31_ RGVLA 36_ CLDGY 41_ MNIAL 46_ EQTEE 51_ YVNGQ 56_ LKNKY 61_ GDAFI 66_ RGNNV 71_LYIST
1: Plays a role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex) (PubMed:28781166). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA (PubMed:10523320). Component of LSm protein complexes, which are involved in RNA processing and may function in a chaperone-like manner, facilitating the efficient association of RNA processing factors with their substrates. Component of the cytoplasmic LSM1-LSM7 complex, which is thought to be involved in mRNA degradation by activating the decapping step in the 5'-to-3' mRNA decay pathway (Probable)