Thioredoxin reductase-like selenoprotein T (SelT) (EC 1.8.1.9)
1_MRLLL 6_ LLLVA 11_ ASAMV 16_ RSEAS 21_ ANLGG 26_ VPSKR 31_ LKMQY 36_ ATGPL 41_ LKFQI 46_ CVSUG 51_ YRRVF 56_ EEYMR 61_ VISQR 66_ YPDIR 71_ IEGEN 76_ YLPQP 81_ IYRHI 86_ ASFLS 91_ VFKLV 96_ LIGLI 101_ IVGKD 106_ PFAFF 111_ GMQAP 116_ SIWQW 121_ GQENK 126_ VYACM 131_ MVFFL 136_ SNMIE 141_ NQCMS 146_ TGAFE 151_ ITLND 156_ VPVWS 161_ KLESG 166_ HLPSM 171_ QQLVQ 176_ ILDNE 181_ MKLNV 186_HMDSI
1: Selenoprotein with thioredoxin reductase-like oxidoreductase activity (By similarity). Protects dopaminergic neurons against oxidative stress and cell death (PubMed:26866473). Involved in ADCYAP1/PACAP-induced calcium mobilization and neuroendocrine secretion (By similarity). Plays a role in fibroblast anchorage and redox regulation (By similarity). In gastric smooth muscle, modulates the contraction processes through the regulation of calcium release and MYLK activation (By similarity). In pancreatic islets, involved in the control of glucose homeostasis, contributes to prolonged ADCYAP1/PACAP-induced insulin secretion (By similarity)