40S ribosomal protein S6 (Phosphoprotein NP33) (Small ribosomal subunit protein eS6)
1_MKLNI 6_ SFPAT 11_ GCQKL 16_ IEVDD 21_ ERKLR 26_ TFYEK 31_ RMATE 36_ VAADA 41_ LGEEW 46_ KGYVV 51_ RISGG 56_ NDKQG 61_ FPMKQ 66_ GVLTH 71_ GRVRL 76_ LLSKG 81_ HSCYR 86_ PRRTG 91_ ERKRK 96_ SVRGC 101_ IVDAN 106_ LSVLN 111_ LVIVK 116_ KGEKD 121_ IPGLT 126_ DTTVP 131_ RRLGP 136_ KRASR 141_ IRKLF 146_ NLSKE 151_ DDVRQ 156_ YVVRK 161_ PLNKE 166_ GKKPR 171_ TKAPK 176_ IQRLV 181_ TPRVL 186_ QHKRR 191_ RIALK 196_ KQRTK 201_ KNKEE 206_ AAEYA 211_ KLLAK 216_ RMKEA 221_ KEKRQ 226_ EQIAK 231_ RRRLS 236_ SLRAS 241_TSKSE
1: Component of the 40S small ribosomal subunit (PubMed:23636399, PubMed:8706699). Plays an important role in controlling cell growth and proliferation through the selective translation of particular classes of mRNA (PubMed:17220279). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)