Gene name: H4C1

Uniprot entry:

P62805

Protein names:

Histone H4

Protein sequence:

1_MSGRG 6_ KGGKG 11_ LGKGG 16_ AKRHR 21_ KVLRD 26_ NIQGI 31_ TKPAI 36_ RRLAR 41_ RGGVK 46_ RISGL 51_ IYEET 56_ RGVLK 61_ VFLEN 66_ VIRDA 71_ VTYTE 76_ HAKRK 81_ TVTAM 86_ DVVYA 91_ LKRQG 96_RTLYG

Protein annotations

Protein functions:

1: Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling