Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B) (EC 5.2.1.8) (12.6 kDa FK506-binding protein) (12.6 kDa FKBP) (FKBP-12.6) (FK506-binding protein 1B) (FKBP-1B) (Immunophilin FKBP12.6) (Rotamase) (h-FKBP-12)
1_MGVEI 6_ ETISP 11_ GDGRT 16_ FPKKG 21_ QTCVV 26_ HYTGM 31_ LQNGK 36_ KFDSS 41_ RDRNK 46_ PFKFR 51_ IGKQE 56_ VIKGF 61_ EEGAA 66_ QMSLG 71_ QRAKL 76_ TCTPD 81_ VAYGA 86_ TGHPG 91_ VIPPN 96_ ATLIF 101_DVELL
1: Has the potential to contribute to the immunosuppressive and toxic effects of FK506 and rapamycin. PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides