Tubulin beta-4B chain (Tubulin beta-2 chain) (Tubulin beta-2C chain)
1_MREIV 6_ HLQAG 11_ QCGNQ 16_ IGAKF 21_ WEVIS 26_ DEHGI 31_ DPTGT 36_ YHGDS 41_ DLQLE 46_ RINVY 51_ YNEAT 56_ GGKYV 61_ PRAVL 66_ VDLEP 71_ GTMDS 76_ VRSGP 81_ FGQIF 86_ RPDNF 91_ VFGQS 96_ GAGNN 101_ WAKGH 106_ YTEGA 111_ ELVDS 116_ VLDVV 121_ RKEAE 126_ SCDCL 131_ QGFQL 136_ THSLG 141_ GGTGS 146_ GMGTL 151_ LISKI 156_ REEYP 161_ DRIMN 166_ TFSVV 171_ PSPKV 176_ SDTVV 181_ EPYNA 186_ TLSVH 191_ QLVEN 196_ TDETY 201_ CIDNE 206_ ALYDI 211_ CFRTL 216_ KLTTP 221_ TYGDL 226_ NHLVS 231_ ATMSG 236_ VTTCL 241_ RFPGQ 246_ LNADL 251_ RKLAV 256_ NMVPF 261_ PRLHF 266_ FMPGF 271_ APLTS 276_ RGSQQ 281_ YRALT 286_ VPELT 291_ QQMFD 296_ AKNMM 301_ AACDP 306_ RHGRY 311_ LTVAA 316_ VFRGR 321_ MSMKE 326_ VDEQM 331_ LNVQN 336_ KNSSY 341_ FVEWI 346_ PNNVK 351_ TAVCD 356_ IPPRG 361_ LKMSA 366_ TFIGN 371_ STAIQ 376_ ELFKR 381_ ISEQF 386_ TAMFR 391_ RKAFL 396_ HWYTG 401_ EGMDE 406_ MEFTE 411_ AESNM 416_ NDLVS 421_ EYQQY 426_ QDATA 431_ EEEGE 436_FEEEA
1: Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule end, where a stabilizing cap forms. Below the cap, tubulin dimers are in GDP-bound state, owing to GTPase activity of alpha-tubulin