Gene name: PSPH

Uniprot entry:

P78330

Protein names:

Phosphoserine phosphatase (PSP) (PSPase) (EC 3.1.3.3) (L-3-phosphoserine phosphatase) (O-phosphoserine phosphohydrolase)

Protein sequence:

1_MVSHS 6_ ELRKL 11_ FYSAD 16_ AVCFD 21_ VDSTV 26_ IREEG 31_ IDELA 36_ KICGV 41_ EDAVS 46_ EMTRR 51_ AMGGA 56_ VPFKA 61_ ALTER 66_ LALIQ 71_ PSREQ 76_ VQRLI 81_ AEQPP 86_ HLTPG 91_ IRELV 96_ SRLQE 101_ RNVQV 106_ FLISG 111_ GFRSI 116_ VEHVA 121_ SKLNI 126_ PATNV 131_ FANRL 136_ KFYFN 141_ GEYAG 146_ FDETQ 151_ PTAES 156_ GGKGK 161_ VIKLL 166_ KEKFH 171_ FKKII 176_ MIGDG 181_ ATDME 186_ ACPPA 191_ DAFIG 196_ FGGNV 201_ IRQQV 206_ KDNAK 211_ WYITD 216_FVELL

Protein annotations

Protein functions:

1: Catalyzes the last irreversible step in the biosynthesis of L-serine from carbohydrates, the dephosphorylation of O-phospho-L-serine to L-serine (PubMed:12213811, PubMed:14673469, PubMed:15291819, PubMed:25080166, PubMed:9222972). L-serine can then be used in protein synthesis, to produce other amino acids, in nucleotide metabolism or in glutathione synthesis, or can be racemized to D-serine, a neuromodulator (PubMed:14673469). May also act on O-phospho-D-serine (Probable)