General transcription factor II-I (GTFII-I) (TFII-I) (Bruton tyrosine kinase-associated protein 135) (BAP-135) (BTK-associated protein 135) (SRF-Phox1-interacting protein) (SPIN) (Williams-Beuren syndrome chromosomal region 6 protein)
1_MAQVA 6_ MSTLP 11_ VEDEE 16_ SSESR 21_ MVVTF 26_ LMSAL 31_ ESMCK 36_ ELAKS 41_ KAEVA 46_ CIAVY 51_ ETDVF 56_ VVGTE 61_ RGRAF 66_ VNTRK 71_ DFQKD 76_ FVKYC 81_ VEEEE 86_ KAAEM 91_ HKMKS 96_ TTQAN 101_ RMSVD 106_ AVEIE 111_ TLRKT 116_ VEDYF 121_ CFCYG 126_ KALGK 131_ STVVP 136_ VPYEK 141_ MLRDQ 146_ SAVVV 151_ QGLPE 156_ GVAFK 161_ HPENY 166_ DLATL 171_ KWILE 176_ NKAGI 181_ SFIIK 186_ RPFLE 191_ PKKHV 196_ GGRVM 201_ VTDAD 206_ RSILS 211_ PGGSC 216_ GPIKV 221_ KTEPT 226_ EDSGI 231_ SLEMA 236_ AVTVK 241_ EESED 246_ PDYYQ 251_ YNIQA 256_ GPSET 261_ DDVDE 266_ KQPLS 271_ KPLQG 276_ SHHSS 281_ EGNEG 286_ TEMEV 291_ PAEDS 296_ TQHVP 301_ SETSE 306_ DPEVE 311_ VTIED 316_ DDYSP 321_ PSKRP 326_ KANEL 331_ PQPPV 336_ PEPAN 341_ AGKRK 346_ VREFN 351_ FEKWN 356_ ARITD 361_ LRKQV 366_ EELFE 371_ RKYAQ 376_ AIKAK 381_ GPVTI 386_ PYPLF 391_ QSHVE 396_ DLYVE 401_ GLPEG 406_ IPFRR 411_ PSTYG 416_ IPRLE 421_ RILLA 426_ KERIR 431_ FVIKK 436_ HELLN 441_ STRED 446_ LQLDK 451_ PASGV 456_ KEEWY 461_ ARITK 466_ LRKMV 471_ DQLFC 476_ KKFAE 481_ ALGST 486_ EAKAV 491_ PYQKF 496_ EAHPN 501_ DLYVE 506_ GLPEN 511_ IPFRS 516_ PSWYG 521_ IPRLE 526_ KIIQV 531_ GNRIK 536_ FVIKR 541_ PELLT 546_ HSTTE 551_ VTQPR 556_ TNTPV 561_ KEDWN 566_ VRITK 571_ LRKQV 576_ EEIFN 581_ LKFAQ 586_ ALGLT 591_ EAVKV 596_ PYPVF 601_ ESNPE 606_ FLYVE 611_ GLPEG 616_ IPFRS 621_ PTWFG 626_ IPRLE 631_ RIVRG 636_ SNKIK 641_ FVVKK 646_ PELVI 651_ SYLPP 656_ GMASK 661_ INTKA 666_ LQSPK 671_ RPRSP 676_ GSNSK 681_ VPEIE 686_ VTVEG 691_ PNNNN 696_ PQTSA 701_ VRTPT 706_ QTNGS 711_ NVPFK 716_ PRGRE 721_ FSFEA 726_ WNAKI 731_ TDLKQ 736_ KVENL 741_ FNEKC 746_ GEALG 751_ LKQAV 756_ KVPFA 761_ LFESF 766_ PEDFY 771_ VEGLP 776_ EGVPF 781_ RRPST 786_ FGIPR 791_ LEKIL 796_ RNKAK 801_ IKFII 806_ KKPEM 811_ FETAI 816_ KESTS 821_ SKSPP 826_ RKINS 831_ SPNVN 836_ TTASG 841_ VEDLN 846_ IIQVT 851_ IPDDD 856_ NERLS 861_ KVEKA 866_ RQLRE 871_ QVNDL 876_ FSRKF 881_ GEAIG 886_ MGFPV 891_ KVPYR 896_ KITIN 901_ PGCVV 906_ VDGMP 911_ PGVSF 916_ KAPSY 921_ LEISS 926_ MRRIL 931_ DSAEF 936_ IKFTV 941_ IRPFP 946_ GLVIN 951_ NQLVD 956_ QSESE 961_ GPVIQ 966_ ESAEP 971_ SQLEV 976_ PATEE 981_ IKETD 986_ GSSQI 991_KQEPD
1: Interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Promotes the formation of stable high-order complexes of SRF and PHOX1 and interacts cooperatively with PHOX1 to promote serum-inducible transcription of a reporter gene deriven by the C-FOS serum response element (SRE). Acts as a coregulator for USF1 by binding independently two promoter elements, a pyrimidine-rich initiator (Inr) and an upstream E-box. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation