UDP-galactose translocator (Solute carrier family 35 member A2) (UDP-galactose transporter) (UDP-Gal-Tr) (UGT)
1_MAAVG 6_ AGGST 11_ AAPGP 16_ GAVSA 21_ GALEP 26_ GTASA 31_ AHRRL 36_ KYISL 41_ AVLVV 46_ QNASL 51_ ILSIR 56_ YARTL 61_ PGDRF 66_ FATTA 71_ VVMAE 76_ VLKGL 81_ TCLLL 86_ LFAQK 91_ RGNVK 96_ HLVLF 101_ LHEAV 106_ LVQYV 111_ DTLKL 116_ AVPSL 121_ IYTLQ 126_ NNLQY 131_ VAISN 136_ LPAAT 141_ FQVTY 146_ QLKIL 151_ TTALF 156_ SVLML 161_ NRSLS 166_ RLQWA 171_ SLLLL 176_ FTGVA 181_ IVQAQ 186_ QAGGG 191_ GPRPL 196_ DQNPG 201_ AGLAA 206_ VVASC 211_ LSSGF 216_ AGVYF 221_ EKILK 226_ GSSGS 231_ VWLRN 236_ LQLGL 241_ FGTAL 246_ GLVGL 251_ WWAEG 256_ TAVAT 261_ RGFFF 266_ GYTPA 271_ VWGVV 276_ LNQAF 281_ GGLLV 286_ AVVVK 291_ YADNI 296_ LKGFA 301_ TSLSI 306_ VLSTV 311_ ASIRL 316_ FGFHV 321_ DPLFA 326_ LGAGL 331_ VIGAV 336_ YLYSL 341_ PRGAA 346_ KAIAS 351_ ASASA 356_ SGPCV 361_ HQQPP 366_ GQPPP 371_ PQLSS 376_ HRGDL 381_ ITEPF 386_ LPKLL 391_TKVKG
1: Transports uridine diphosphate galactose (UDP-galactose) from the cytosol into the Golgi apparatus, functioning as an antiporter that exchanges UDP-galactose for UMP (PubMed:12682060, PubMed:9010752). It is also able to exchange UDP-galactose for AMP and CMP, and to transport UDP-N-acetylgalactosamine (UDP-GalNAc) and other nucleotide sugars (PubMed:11784306, PubMed:12682060). As a provider of UDP-galactose to galactosyltransferases present in the Golgi apparatus, it is necessary for globotriaosylceramide/globoside (Gb3Cer) synthesis from lactosylceramide (PubMed:30817854)