C-C motif chemokine 8 (HC14) (Monocyte chemoattractant protein 2) (Monocyte chemotactic protein 2) (MCP-2) (Small-inducible cytokine A8) [Cleaved into: MCP-2(6-76)]
1_MKVSA 6_ ALLCL 11_ LLMAA 16_ TFSPQ 21_ GLAQP 26_ DSVSI 31_ PITCC 36_ FNVIN 41_ RKIPI 46_ QRLES 51_ YTRIT 56_ NIQCP 61_ KEAVI 66_ FKTKR 71_ GKEVC 76_ ADPKE 81_ RWVRD 86_ SMKHL 91_DQIFQ
1: Chemotactic factor that attracts monocytes, lymphocytes, basophils and eosinophils. May play a role in neoplasia and inflammatory host responses. This protein can bind heparin. The processed form MCP-2(6-76) does not show monocyte chemotactic activity, but inhibits the chemotactic effect most predominantly of CCL7, and also of CCL2 and CCL5 and CCL8