Gene name: CYCS

Uniprot entry:

P99999

Protein names:

Cytochrome c

Protein sequence:

1_MGDVE 6_ KGKKI 11_ FIMKC 16_ SQCHT 21_ VEKGG 26_ KHKTG 31_ PNLHG 36_ LFGRK 41_ TGQAP 46_ GYSYT 51_ AANKN 56_ KGIIW 61_ GEDTL 66_ MEYLE 71_ NPKKY 76_ IPGTK 81_ MIFVG 86_ IKKKE 91_ ERADL 96_IAYLK

Protein annotations

Protein functions:

1: Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain

2: Plays a role in apoptosis. Suppression of the anti-apoptotic members or activation of the pro-apoptotic members of the Bcl-2 family leads to altered mitochondrial membrane permeability resulting in release of cytochrome c into the cytosol. Binding of cytochrome c to Apaf-1 triggers the activation of caspase-9, which then accelerates apoptosis by activating other caspases