Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B beta isoform (PP2A subunit B isoform B55-beta) (PP2A subunit B isoform PR55-beta) (PP2A subunit B isoform R2-beta) (PP2A subunit B isoform beta)
1_MEEDI 6_ DTRKI 11_ NNSFL 16_ RDHSY 21_ ATEAD 26_ IISTV 31_ EFNHT 36_ GELLA 41_ TGDKG 46_ GRVVI 51_ FQREQ 56_ ESKNQ 61_ VHRRG 66_ EYNVY 71_ STFQS 76_ HEPEF 81_ DYLKS 86_ LEIEE 91_ KINKI 96_ RWLPQ 101_ QNAAY 106_ FLLST 111_ NDKTV 116_ KLWKV 121_ SERDK 126_ RPEGY 131_ NLKDE 136_ EGRLR 141_ DPATI 146_ TTLRV 151_ PVLRP 156_ MDLMV 161_ EATPR 166_ RVFAN 171_ AHTYH 176_ INSIS 181_ VNSDY 186_ ETYMS 191_ ADDLR 196_ INLWN 201_ FEITN 206_ QSFNI 211_ VDIKP 216_ ANMEE 221_ LTEVI 226_ TAAEF 231_ HPHHC 236_ NTFVY 241_ SSSKG 246_ TIRLC 251_ DMRAS 256_ ALCDR 261_ HTKFF 266_ EEPED 271_ PSNRS 276_ FFSEI 281_ ISSIS 286_ DVKFS 291_ HSGRY 296_ IMTRD 301_ YLTVK 306_ VWDLN 311_ MENRP 316_ IETYQ 321_ VHDYL 326_ RSKLC 331_ SLYEN 336_ DCIFD 341_ KFECV 346_ WNGSD 351_ SVIMT 356_ GSYNN 361_ FFRMF 366_ DRNTK 371_ RDVTL 376_ EASRE 381_ NSKPR 386_ AILKP 391_ RKVCV 396_ GGKRR 401_ KDEIS 406_ VDSLD 411_ FSKKI 416_ LHTAW 421_ HPSEN 426_ IIAVA 431_ ATNNL 436_YIFQD
1: The B regulatory subunit might modulate substrate selectivity and catalytic activity, and might also direct the localization of the catalytic enzyme to a particular subcellular compartment. Within the PP2A holoenzyme complex, isoform 2 is required to promote proapoptotic activity (By similarity). Isoform 2 regulates neuronal survival through the mitochondrial fission and fusion balance (By similarity)