Phosphatidylinositol transfer protein alpha isoform (PI-TP-alpha) (PtdIns transfer protein alpha) (PtdInsTP alpha)
1_MVLLK 6_ EYRVI 11_ LPVSV 16_ DEYQV 21_ GQLYS 26_ VAEAS 31_ KNETG 36_ GGEGV 41_ EVLVN 46_ EPYEK 51_ DGEKG 56_ QYTHK 61_ IYHLQ 66_ SKVPT 71_ FVRML 76_ APEGA 81_ LNIHE 86_ KAWNA 91_ YPYCR 96_ TVITN 101_ EYMKE 106_ DFLIK 111_ IETWH 116_ KPDLG 121_ TQENV 126_ HKLEP 131_ EAWKH 136_ VEAVY 141_ IDIAD 146_ RSQVL 151_ SKDYK 156_ AEEDP 161_ AKFKS 166_ IKTGR 171_ GPLGP 176_ NWKQE 181_ LVNQK 186_ DCPYM 191_ CAYKL 196_ VTVKF 201_ KWWGL 206_ QNKVE 211_ NFIHK 216_ QERRL 221_ FTNFH 226_ RQLFC 231_ WLDKW 236_ VDLTM 241_ DDIRR 246_ MEEET 251_ KRQLD 256_ EMRQK 261_DPVKG
1: Catalyzes the transfer of phosphatidylinositol (PI) and phosphatidylcholine (PC) between membranes (PubMed:10531358, PubMed:14962392, PubMed:15522822, PubMed:18636990, PubMed:22822086). Shows a preference for PI and PC containing shorter saturated or monosaturated acyl chains at the sn-1 and sn-2 positions (PubMed:15522822, PubMed:22822086). Preference order for PC is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 and for PI is C16:1 > C16:0 > C18:1 > C18:0 > C20:4 > C20:3 (PubMed:22822086)