S-adenosylmethionine synthase isoform type-1 (AdoMet synthase 1) (EC 2.5.1.6) (Methionine adenosyltransferase 1) (MAT 1) (Methionine adenosyltransferase I/III) (MAT-I/III)
1_MNGPV 6_ DGLCD 11_ HSLSE 16_ GVFMF 21_ TSESV 26_ GEGHP 31_ DKICD 36_ QISDA 41_ VLDAH 46_ LKQDP 51_ NAKVA 56_ CETVC 61_ KTGMV 66_ LLCGE 71_ ITSMA 76_ MVDYQ 81_ RVVRD 86_ TIKHI 91_ GYDDS 96_ AKGFD 101_ FKTCN 106_ VLVAL 111_ EQQSP 116_ DIAQC 121_ VHLDR 126_ NEEDV 131_ GAGDQ 136_ GLMFG 141_ YATDE 146_ TEECM 151_ PLTII 156_ LAHKL 161_ NARMA 166_ DLRRS 171_ GLLPW 176_ LRPDS 181_ KTQVT 186_ VQYMQ 191_ DNGAV 196_ IPVRI 201_ HTIVI 206_ SVQHN 211_ EDITL 216_ EEMRR 221_ ALKEQ 226_ VIRAV 231_ VPAKY 236_ LDEDT 241_ VYHLQ 246_ PSGRF 251_ VIGGP 256_ QGDAG 261_ VTGRK 266_ IIVDT 271_ YGGWG 276_ AHGGG 281_ AFSGK 286_ DYTKV 291_ DRSAA 296_ YAARW 301_ VAKSL 306_ VKAGL 311_ CRRVL 316_ VQVSY 321_ AIGVA 326_ EPLSI 331_ SIFTY 336_ GTSQK 341_ TEREL 346_ LDVVH 351_ KNFDL 356_ RPGVI 361_ VRDLD 366_ LKKPI 371_ YQKTA 376_ CYGHF 381_ GRSEF 386_PWEVP
1: Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate