Cyclin-dependent kinase 16 (EC 2.7.11.22) (Cell division protein kinase 16) (PCTAIRE-motif protein kinase 1) (Serine/threonine-protein kinase PCTAIRE-1)
1_MDRMK 6_ KIKRQ 11_ LSMTL 16_ RGGRG 21_ IDKTN 26_ GAPEQ 31_ IGLDE 36_ SGGGG 41_ GSDPG 46_ EAPTR 51_ AAPGE 56_ LRSAR 61_ GPLSS 66_ APEIV 71_ HEDLK 76_ MGSDG 81_ ESDQA 86_ SATSS 91_ DEVQS 96_ PVRVR 101_ MRNHP 106_ PRKIS 111_ TEDIN 116_ KRLSL 121_ PADIR 126_ LPEGY 131_ LEKLT 136_ LNSPI 141_ FDKPL 146_ SRRLR 151_ RVSLS 156_ EIGFG 161_ KLETY 166_ IKLDK 171_ LGEGT 176_ YATVY 181_ KGKSK 186_ LTDNL 191_ VALKE 196_ IRLEH 201_ EEGAP 206_ CTAIR 211_ EVSLL 216_ KDLKH 221_ ANIVT 226_ LHDII 231_ HTEKS 236_ LTLVF 241_ EYLDK 246_ DLKQY 251_ LDDCG 256_ NIINM 261_ HNVKL 266_ FLFQL 271_ LRGLA 276_ YCHRQ 281_ KVLHR 286_ DLKPQ 291_ NLLIN 296_ ERGEL 301_ KLADF 306_ GLARA 311_ KSIPT 316_ KTYSN 321_ EVVTL 326_ WYRPP 331_ DILLG 336_ STDYS 341_ TQIDM 346_ WGVGC 351_ IFYEM 356_ ATGRP 361_ LFPGS 366_ TVEEQ 371_ LHFIF 376_ RILGT 381_ PTEET 386_ WPGIL 391_ SNEEF 396_ KTYNY 401_ PKYRA 406_ EALLS 411_ HAPRL 416_ DSDGA 421_ DLLTK 426_ LLQFE 431_ GRNRI 436_ SAEDA 441_ MKHPF 446_ FLSLG 451_ ERIHK 456_ LPDTT 461_ SIFAL 466_ KEIQL 471_ QKEAS 476_ LRSSS 481_ MPDSG 486_ RPAFR 491_VVDTE
1: Protein kinase that plays a role in vesicle-mediated transport processes and exocytosis. Regulates GH1 release by brain neurons. Phosphorylates NSF, and thereby regulates NSF oligomerization. Required for normal spermatogenesis. Regulates neuron differentiation and dendrite development (By similarity). Plays a role in the regulation of insulin secretion in response to changes in blood glucose levels. Can phosphorylate CCNY at 'Ser-336' (in vitro)