Transcriptional activator protein Pur-alpha (Purine-rich single-stranded DNA-binding protein alpha)
1_MADRD 6_ SGSEQ 11_ GGAAL 16_ GSGGS 21_ LGHPG 26_ SGSGS 31_ GGGGG 36_ GGGGG 41_ GGSGG 46_ GGGGA 51_ PGGLQ 56_ HETQE 61_ LASKR 66_ VDIQN 71_ KRFYL 76_ DVKQN 81_ AKGRF 86_ LKIAE 91_ VGAGG 96_ NKSRL 101_ TLSMS 106_ VAVEF 111_ RDYLG 116_ DFIEH 121_ YAQLG 126_ PSQPP 131_ DLAQA 136_ QDEPR 141_ RALKS 146_ EFLVR 151_ ENRKY 156_ YMDLK 161_ ENQRG 166_ RFLRI 171_ RQTVN 176_ RGPGL 181_ GSTQG 186_ QTIAL 191_ PAQGL 196_ IEFRD 201_ ALAKL 206_ IDDYG 211_ VEEEP 216_ AELPE 221_ GTSLT 226_ VDNKR 231_ FFFDV 236_ GSNKY 241_ GVFMR 246_ VSEVK 251_ PTYRN 256_ SITVP 261_ YKVWA 266_ KFGHT 271_ FCKYS 276_ EEMKK 281_ IQEKQ 286_ REKRA 291_ ACEQL 296_ HQQQQ 301_ QQQEE 306_ TAAAT 311_ LLLQG 316_EEEGE
1: This is a probable transcription activator that specifically binds the purine-rich single strand of the PUR element located upstream of the MYC gene (PubMed:1448097, PubMed:20976240). May play a role in the initiation of DNA replication and in recombination