Peptidyl-prolyl cis-trans isomerase FKBP3 (PPIase FKBP3) (EC 5.2.1.8) (25 kDa FK506-binding protein) (25 kDa FKBP) (FKBP-25) (FK506-binding protein 3) (FKBP-3) (Immunophilin FKBP25) (Rapamycin-selective 25 kDa immunophilin) (Rotamase)
1_MAAAV 6_ PQRAW 11_ TVEQL 16_ RSEQL 21_ PKKDI 26_ IKFLQ 31_ EHGSD 36_ SFLAE 41_ HKLLG 46_ NIKNV 51_ AKTAN 56_ KDHLV 61_ TAYNH 66_ LFETK 71_ RFKGT 76_ ESISK 81_ VSEQV 86_ KNVKL 91_ NEDKP 96_ KETKS 101_ EETLD 106_ EGPPK 111_ YTKSV 116_ LKKGD 121_ KTNFP 126_ KKGDV 131_ VHCWY 136_ TGTLQ 141_ DGTVF 146_ DTNIQ 151_ TSAKK 156_ KKNAK 161_ PLSFK 166_ VGVGK 171_ VIRGW 176_ DEALL 181_ TMSKG 186_ EKARL 191_ EIEPE 196_ WAYGK 201_ KGQPD 206_ AKIPP 211_ NAKLT 216_FEVEL
1: FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins