Protein BEX3 (Brain-expressed X-linked protein 3) (Nerve growth factor receptor-associated protein 1) (Ovarian granulosa cell 13.0 kDa protein HGR74) (p75NTR-associated cell death executor)
1_MANIH 6_ QENEE 11_ MEQPM 16_ QNGEE 21_ DRPLG 26_ GGEGH 31_ QPAGN 36_ RRGQA 41_ RRLAP 46_ NFRWA 51_ IPNRQ 56_ INDGM 61_ GGDGD 66_ DMEIF 71_ MEEMR 76_ EIRRK 81_ LRELQ 86_ LRNCL 91_ RILMG 96_ ELSNH 101_ HDHHD 106_EFCLM
1: May be a signaling adapter molecule involved in NGFR/p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. In absence of reductive stress, acts as a pseudosubstrate for the CRL2(FEM1B) complex: associates with FEM1B via zinc, thereby preventing association between FEM1B and its substrates