Splicing factor U2AF 35 kDa subunit (U2 auxiliary factor 35 kDa subunit) (U2 small nuclear RNA auxiliary factor 1) (U2 snRNP auxiliary factor small subunit)
1_MAEYL 6_ ASIFG 11_ TEKDK 16_ VNCSF 21_ YFKIG 26_ ACRHG 31_ DRCSR 36_ LHNKP 41_ TFSQT 46_ IALLN 51_ IYRNP 56_ QNSSQ 61_ SADGL 66_ RCAVS 71_ DVEMQ 76_ EHYDE 81_ FFEEV 86_ FTEME 91_ EKYGE 96_ VEEMN 101_ VCDNL 106_ GDHLV 111_ GNVYV 116_ KFRRE 121_ EDAEK 126_ AVIDL 131_ NNRWF 136_ NGQPI 141_ HAELS 146_ PVTDF 151_ REACC 156_ RQYEM 161_ GECTR 166_ GGFCN 171_ FMHLK 176_ PISRE 181_ LRREL 186_ YGRRR 191_ KKHRS 196_ RSRSR 201_ ERRSR 206_ SRDRG 211_ RGGGG 216_ GGGGG 221_ GGGRE 226_ RDRRR 231_SRDRE
1: Plays a critical role in both constitutive and enhancer-dependent splicing by mediating protein-protein interactions and protein-RNA interactions required for accurate 3'-splice site selection. Recruits U2 snRNP to the branch point. Directly mediates interactions between U2AF2 and proteins bound to the enhancers and thus may function as a bridge between U2AF2 and the enhancer complex to recruit it to the adjacent intron