Voltage-dependent L-type calcium channel subunit alpha-1D (Calcium channel, L type, alpha-1 polypeptide, isoform 2) (Voltage-gated calcium channel subunit alpha Cav1.3)
1_MMMMM 6_ MMKKM 11_ QHQRQ 16_ QQADH 21_ ANEAN 26_ YARGT 31_ RLPLS 36_ GEGPT 41_ SQPNS 46_ SKQTV 51_ LSWQA 56_ AIDAA 61_ RQAKA 66_ AQTMS 71_ TSAPP 76_ PVGSL 81_ SQRKR 86_ QQYAK 91_ SKKQG 96_ NSSNS 101_ RPARA 106_ LFCLS 111_ LNNPI 116_ RRACI 121_ SIVEW 126_ KPFDI 131_ FILLA 136_ IFANC 141_ VALAI 146_ YIPFP 151_ EDDSN 156_ STNHN 161_ LEKVE 166_ YAFLI 171_ IFTVE 176_ TFLKI 181_ IAYGL 186_ LLHPN 191_ AYVRN 196_ GWNLL 201_ DFVIV 206_ IVGLF 211_ SVILE 216_ QLTKE 221_ TEGGN 226_ HSSGK 231_ SGGFD 236_ VKALR 241_ AFRVL 246_ RPLRL 251_ VSGVP 256_ SLQVV 261_ LNSII 266_ KAMVP 271_ LLHIA 276_ LLVLF 281_ VIIIY 286_ AIIGL 291_ ELFIG 296_ KMHKT 301_ CFFAD 306_ SDIVA 311_ EEDPA 316_ PCAFS 321_ GNGRQ 326_ CTANG 331_ TECRS 336_ GWVGP 341_ NGGIT 346_ NFDNF 351_ AFAML 356_ TVFQC 361_ ITMEG 366_ WTDVL 371_ YWMND 376_ AMGFE 381_ LPWVY 386_ FVSLV 391_ IFGSF 396_ FVLNL 401_ VLGVL 406_ SGEFS 411_ KEREK 416_ AKARG 421_ DFQKL 426_ REKQQ 431_ LEEDL 436_ KGYLD 441_ WITQA 446_ EDIDP 451_ ENEEE 456_ GGEEG 461_ KRNTS 466_ MPTSE 471_ TESVN 476_ TENVS 481_ GEGEN 486_ RGCCG 491_ SLCQA 496_ ISKSK 501_ LSRRW 506_ RRWNR 511_ FNRRR 516_ CRAAV 521_ KSVTF 526_ YWLVI 531_ VLVFL 536_ NTLTI 541_ SSEHY 546_ NQPDW 551_ LTQIQ 556_ DIANK 561_ VLLAL 566_ FTCEM 571_ LVKMY 576_ SLGLQ 581_ AYFVS 586_ LFNRF 591_ DCFVV 596_ CGGIT 601_ ETILV 606_ ELEIM 611_ SPLGI 616_ SVFRC 621_ VRLLR 626_ IFKVT 631_ RHWTS 636_ LSNLV 641_ ASLLN 646_ SMKSI 651_ ASLLL 656_ LLFLF 661_ IIIFS 666_ LLGMQ 671_ LFGGK 676_ FNFDE 681_ TQTKR 686_ STFDN 691_ FPQAL 696_ LTVFQ 701_ ILTGE 706_ DWNAV 711_ MYDGI 716_ MAYGG 721_ PSSSG 726_ MIVCI 731_ YFIIL 736_ FICGN 741_ YILLN 746_ VFLAI 751_ AVDNL 756_ ADAES 761_ LNTAQ 766_ KEEAE 771_ EKERK 776_ KIARK 781_ ESLEN 786_ KKNNK 791_ PEVNQ 796_ IANSD 801_ NKVTI 806_ DDYRE 811_ EDEDK 816_ DPYPP 821_ CDVPV 826_ GEEEE 831_ EEEED 836_ EPEVP 841_ AGPRP 846_ RRISE 851_ LNMKE 856_ KIAPI 861_ PEGSA 866_ FFILS 871_ KTNPI 876_ RVGCH 881_ KLINH 886_ HIFTN 891_ LILVF 896_ IMLSS 901_ AALAA 906_ EDPIR 911_ SHSFR 916_ NTILG 921_ YFDYA 926_ FTAIF 931_ TVEIL 936_ LKMTT 941_ FGAFL 946_ HKGAF 951_ CRNYF 956_ NLLDM 961_ LVVGV 966_ SLVSF 971_ GIQSS 976_ AISVV 981_ KILRV 986_ LRVLR 991_ PLRAI 996_ NRAKG 1001_ LKHVV 1006_ QCVFV 1011_ AIRTI 1016_ GNIMI 1021_ VTTLL 1026_ QFMFA 1031_ CIGVQ 1036_ LFKGK 1041_ FYRCT 1046_ DEAKS 1051_ NPEEC 1056_ RGLFI 1061_ LYKDG 1066_ DVDSP 1071_ VVRER 1076_ IWQNS 1081_ DFNFD 1086_ NVLSA 1091_ MMALF 1096_ TVSTF 1101_ EGWPA 1106_ LLYKA 1111_ IDSNG 1116_ ENIGP 1121_ IYNHR 1126_ VEISI 1131_ FFIIY 1136_ IIIVA 1141_ FFMMN 1146_ IFVGF 1151_ VIVTF 1156_ QEQGE 1161_ KEYKN 1166_ CELDK 1171_ NQRQC 1176_ VEYAL 1181_ KARPL 1186_ RRYIP 1191_ KNPYQ 1196_ YKFWY 1201_ VVNSS 1206_ PFEYM 1211_ MFVLI 1216_ MLNTL 1221_ CLAMQ 1226_ HYEQS 1231_ KMFND 1236_ AMDIL 1241_ NMVFT 1246_ GVFTV 1251_ EMVLK 1256_ VIAFK 1261_ PKGYF 1266_ SDAWN 1271_ TFDSL 1276_ IVIGS 1281_ IIDVA 1286_ LSEAD 1291_ PTESE 1296_ NVPVP 1301_ TATPG 1306_ NSEES 1311_ NRISI 1316_ TFFRL 1321_ FRVMR 1326_ LVKLL 1331_ SRGEG 1336_ IRTLL 1341_ WTFIK 1346_ SFQAL 1351_ PYVAL 1356_ LIAML 1361_ FFIYA 1366_ VIGMQ 1371_ MFGKV 1376_ AMRDN 1381_ NQINR 1386_ NNNFQ 1391_ TFPQA 1396_ VLLLF 1401_ RCATG 1406_ EAWQE 1411_ IMLAC 1416_ LPGKL 1421_ CDPES 1426_ DYNPG 1431_ EEYTC 1436_ GSNFA 1441_ IVYFI 1446_ SFYML 1451_ CAFLI 1456_ INLFV 1461_ AVIMD 1466_ NFDYL 1471_ TRDWS 1476_ ILGPH 1481_ HLDEF 1486_ KRIWS 1491_ EYDPE 1496_ AKGRI 1501_ KHLDV 1506_ VTLLR 1511_ RIQPP 1516_ LGFGK 1521_ LCPHR 1526_ VACKR 1531_ LVAMN 1536_ MPLNS 1541_ DGTVM 1546_ FNATL 1551_ FALVR 1556_ TALKI 1561_ KTEGN 1566_ LEQAN 1571_ EELRA 1576_ VIKKI 1581_ WKKTS 1586_ MKLLD 1591_ QVVPP 1596_ AGDDE 1601_ VTVGK 1606_ FYATF 1611_ LIQDY 1616_ FRKFK 1621_ KRKEQ 1626_ GLVGK 1631_ YPAKN 1636_ TTIAL 1641_ QAGLR 1646_ TLHDI 1651_ GPEIR 1656_ RAISC 1661_ DLQDD 1666_ EPEET 1671_ KREEE 1676_ DDVFK 1681_ RNGAL 1686_ LGNHV 1691_ NHVNS 1696_ DRRDS 1701_ LQQTN 1706_ TTHRP 1711_ LHVQR 1716_ PSIPP 1721_ ASDTE 1726_ KPLFP 1731_ PAGNS 1736_ VCHNH 1741_ HNHNS 1746_ IGKQV 1751_ PTSTN 1756_ ANLNN 1761_ ANMSK 1766_ AAHGK 1771_ RPSIG 1776_ NLEHV 1781_ SENGH 1786_ HSSHK 1791_ HDREP 1796_ QRRSS 1801_ VKRTR 1806_ YYETY 1811_ IRSDS 1816_ GDEQL 1821_ PTICR 1826_ EDPEI 1831_ HGYFR 1836_ DPHCL 1841_ GEQEY 1846_ FSSEE 1851_ CYEDD 1856_ SSPTW 1861_ SRQNY 1866_ GYYSR 1871_ YPGRN 1876_ IDSER 1881_ PRGYH 1886_ HPQGF 1891_ LEDDD 1896_ SPVCY 1901_ DSRRS 1906_ PRRRL 1911_ LPPTP 1916_ ASHRR 1921_ SSFNF 1926_ ECLRR 1931_ QSSQE 1936_ EVPSS 1941_ PIFPH 1946_ RTALP 1951_ LHLMQ 1956_ QQIMA 1961_ VAGLD 1966_ SSKAQ 1971_ KYSPS 1976_ HSTRS 1981_ WATPP 1986_ ATPPY 1991_ RDWTP 1996_ CYTPL 2001_ IQVEQ 2006_ SEALD 2011_ QVNGS 2016_ LPSLH 2021_ RSSWY 2026_ TDEPD 2031_ ISYRT 2036_ FTPAS 2041_ LTVPS 2046_ SFRNK 2051_ NSDKQ 2056_ RSADS 2061_ LVEAV 2066_ LISEG 2071_ LGRYA 2076_ RDPKF 2081_ VSATK 2086_ HEIAD 2091_ ACDLT 2096_ IDEME 2101_ SAAST 2106_ LLNGN 2111_ VRPRA 2116_ NGDVG 2121_ PLSHR 2126_ QDYEL 2131_ QDFGP 2136_ GYSDE 2141_ EPDPG 2146_ RDEED 2151_ LADEM 2156_ICITT
1: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents. Long-lasting (L-type) calcium channels belong to the 'high-voltage activated' (HVA) group. They are blocked by dihydropyridines (DHP), phenylalkylamines, and by benzothiazepines
2: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents
3: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents
4: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1D gives rise to L-type calcium currents