Dihydroorotate dehydrogenase (quinone), mitochondrial (DHOdehase) (EC 1.3.5.2) (Dihydroorotate oxidase)
1_MAWRH 6_ LKKRA 11_ QDAVI 16_ ILGGG 21_ GLLFA 26_ SYLMA 31_ TGDER 36_ FYAEH 41_ LMPTL 46_ QGLLD 51_ PESAH 56_ RLAVR 61_ FTSLG 66_ LLPRA 71_ RFQDS 76_ DMLEV 81_ RVLGH 86_ KFRNP 91_ VGIAA 96_ GFDKH 101_ GEAVD 106_ GLYKM 111_ GFGFV 116_ EIGSV 121_ TPKPQ 126_ EGNPR 131_ PRVFR 136_ LPEDQ 141_ AVINR 146_ YGFNS 151_ HGLSV 156_ VEHRL 161_ RARQQ 166_ KQAKL 171_ TEDGL 176_ PLGVN 181_ LGKNK 186_ TSVDA 191_ AEDYA 196_ EGVRV 201_ LGPLA 206_ DYLVV 211_ NVSSP 216_ NTAGL 221_ RSLQG 226_ KAELR 231_ RLLTK 236_ VLQER 241_ DGLRR 246_ VHRPA 251_ VLVKI 256_ APDLT 261_ SQDKE 266_ DIASV 271_ VKELG 276_ IDGLI 281_ VTNTT 286_ VSRPA 291_ GLQGA 296_ LRSET 301_ GGLSG 306_ KPLRD 311_ LSTQT 316_ IREMY 321_ ALTQG 326_ RVPII 331_ GVGGV 336_ SSGQD 341_ ALEKI 346_ RAGAS 351_ LVQLY 356_ TALTF 361_ WGPPV 366_ VGKVK 371_ RELEA 376_ LLKEQ 381_ GFGGV 386_TDAIG
1: Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor. Required for UMP biosynthesis via de novo pathway